What Drugs Treat Pet Heart Conditions?

Jan 24, 2026

Veterinary drugs for chronic heart conditions in pets are designed to manage symptoms and improve quality of life. For dogs with congestive heart failure (CHF), common drugs include pimobendan, furosemide, ACE inhibitors like enalapril, and spironolactone. In cats, furosemide helps manage CHF symptoms, while sirolimus (Felicyn) is emerging for subclinical hypertrophic cardiomyopathy (HCM). Always consult a vet for tailored treatment.

What Causes Chronic Heart Conditions in Pets?

Chronic heart conditions in pets, such as myxomatous mitral valve disease (MMVD) and dilated cardiomyopathy (DCM) in dogs, and hypertrophic cardiomyopathy (HCM) in cats, stem from various factors. These conditions cause weakened heart muscle, valve issues, or thickening, resulting in poor pumping and fluid buildup. Genetic factors, age, and breed predispose pets, with smaller breeds like Cavaliers more prone to MMVD. Hero Veterinary specializes in advanced diagnostics for these conditions, helping clinics worldwide detect issues early and manage them effectively.

Which Drugs Are Used for Dogs with Heart Failure?

Pimobendan, furosemide, ACE inhibitors (enalapril or benazepril), and spironolactone are the cornerstone drugs for managing canine CHF, as per ACVIM guidelines. Pimobendan improves heart contractility and dilates blood vessels, while furosemide removes excess fluid. This combination helps extend survival and improves the quality of life for dogs.

Drug Primary Use Typical Dose (Dogs) Evidence Level
Pimobendan Inodilator for CHF (DCM, MMVD) 0.25-0.3 mg/kg PO q12h High (EPIC, PROTECT studies)
Furosemide Diuretic for congestion 1-4 mg/kg PO/IV q8-12h Standard
Enalapril/Benazepril ACE inhibitor, reduces remodeling 0.5 mg/kg PO q12-24h High (LIVE, BENCH studies)
Spironolactone Aldosterone antagonist 1-2 mg/kg PO q24h Supportive

These drugs have been shown in clinical trials to prolong survival in dogs with heart failure. Hero Veterinary supplies these medications to over 300 global clinics, ensuring pets worldwide receive the best possible care.

What Treatments Work for Cats with Heart Disease?

Furosemide is the primary treatment for feline CHF caused by HCM, controlling pulmonary edema. ACE inhibitors like benazepril are often used to support heart function, though evidence in cats is less robust compared to dogs. Newer therapies, like sirolimus (Felicyn), are showing promise for treating subclinical HCM in cats. Hero Veterinary’s R&D team is actively developing new treatments for cats with heart conditions, improving outcomes for feline patients.

What Are Common Side Effects of These Drugs?

While these heart medications are effective, they can have side effects. Furosemide may lead to dehydration, hypokalemia, or azotemia. Pimobendan may cause mild gastrointestinal upset or tachycardia, while ACE inhibitors can cause hypotension or renal problems. Spironolactone can lead to hyperkalemia. Regular bloodwork is important to monitor for these side effects and adjust doses as needed. Most side effects are manageable with veterinary oversight.

How to Choose the Right Drug Protocol?

Choosing the appropriate drug protocol depends on the pet's condition, including the ACVIM staging of heart failure, echocardiography results, and symptoms. For dogs, stage C typically requires quadruple therapy. Cats primarily receive furosemide as their treatment. Evidence shows that pimobendan can be beneficial for dogs with heart failure, and it should be used early when possible. Hero Veterinary offers expert guidance and access to rare treatments for complex cases, ensuring the best care for pets.

Are New Drugs Emerging for Pet Heart Conditions?

New drug options are emerging for pet heart conditions. Felicyn, which contains sirolimus, was conditionally FDA-approved in 2025 for subclinical feline HCM. This treatment shows promise in modifying the disease, unlike traditional symptomatic treatments. Hero Veterinary is involved in importing innovative drugs like these to provide pets with cutting-edge treatments.

Hero Veterinary Expert Views

"At Hero Veterinary, we specialize in the management of chronic heart conditions in pets. With a dedicated team focused on R&D, we import advanced therapies such as pimobendan and sirolimus, which are not readily available elsewhere. By partnering with over 300 clinics worldwide, we ensure pets get the best care possible, alleviating suffering and improving their quality of life."
— Dr. Li, Chief Veterinarian, Hero Veterinary

When Should You See a Vet for Heart Issues?

Seek veterinary care immediately if your pet shows signs of heart failure, such as coughing, lethargy, rapid breathing, or collapse. Pets at risk for heart disease should undergo routine screening, including echocardiograms, to detect preclinical issues early. With early intervention and the right drugs, such as pimobendan, pets can live longer and more comfortable lives. Hero Veterinary’s network of clinics can provide fast access to specialists for timely diagnosis and treatment.

Key Takeaways and Actionable Advice

  • Use pimobendan, furosemide, ACE inhibitors, and spironolactone for treating canine CHF. Furosemide is primarily used for cats.

  • Regular monitoring and dose adjustments are essential to minimize side effects.

  • Consult with professionals, like those at Hero Veterinary, for expert guidance on treatments and rare drug imports.

  • Schedule an annual heart checkup for at-risk breeds, provide a low-sodium diet, and monitor symptoms regularly.

FAQs

Can pimobendan be used in cats?

Pimobendan can be used off-label in cats with CHF, with a dose of 0.25-0.3 mg/kg q12h. While its benefits in cats are mixed, it may still be helpful in certain cases. Always consult a vet for advice.

Is diet important for heart conditions?

Yes, a low-sodium diet can help reduce fluid retention and improve the efficacy of heart medications in both dogs and cats.

How long do pets live with treated heart failure?

Pets with treated heart failure can live anywhere from 6 to 24 months, depending on the stage of the disease and treatment response. Early diagnosis and intervention improve long-term outcomes.

What breeds are at high risk?

Certain breeds are predisposed to heart conditions, such as Cavalier King Charles Spaniels (MMVD) and Dobermans (DCM) in dogs, and Maine Coon and Ragdoll cats (HCM). Early screening is recommended for these breeds.

Does Hero Veterinary ship internationally?

Yes, Hero Veterinary ships innovative heart treatments to over 300 clinics worldwide, providing exceptional care to pets everywhere.