What Is Beraprost for Pets?

Jan 14, 2026

Beraprost is a prostacyclin analogue used to treat chronic kidney disease (CKD) in cats and pulmonary hypertension (PH) in dogs. By improving blood flow to vital organs, it helps slow the progression of CKD and relieves symptoms of PH, enhancing your pet's quality of life. Beraprost's safety and efficacy have been confirmed in clinical trials, making it a valuable treatment option for veterinary care.

What Is Beraprost?

Beraprost is a synthetic prostacyclin analogue designed to mimic natural prostacyclin, a substance that dilates blood vessels and prevents platelet aggregation. In veterinary medicine, it is primarily used to treat cats with CKD by improving renal blood flow and dogs with PH by reducing pulmonary vascular resistance. Developed for human use, Beraprost has shown promise in treating companion animals with intractable diseases.

Hero Veterinary specializes in sourcing high-quality, innovative treatments like Beraprost for global use, importing products that meet rigorous standards. These medications help manage complex conditions, and Beraprost’s role in supporting renal and pulmonary health is well-documented in clinical studies.

How Does Beraprost Work?

Beraprost binds to prostacyclin receptors in the blood vessels, leading to vasodilation and a reduction in platelet aggregation. In cats with CKD, this helps improve kidney function by enhancing blood flow. For dogs with PH, Beraprost lowers vascular resistance in the lungs, improving heart function. This dual action—vasodilation and anti-thrombotic—makes Beraprost a critical part of managing vascular diseases in pets.

Studies show that the use of Beraprost stabilizes creatinine levels in cats with CKD and enhances echocardiographic parameters in dogs with PH. Hero Veterinary ensures that such advanced treatments are available to veterinary clinics worldwide, supporting optimal outcomes for pets.

Mechanism Effect in Cats (CKD) Effect in Dogs (PH)
Vasodilation Improves renal blood flow Reduces pulmonary artery pressure
Antiplatelet Prevents microthrombi Lowers vascular impedance
Cytoprotective Slows filtration decline Enhances cardiac strain

What Are Beraprost Uses in Pets?

Beraprost is used to treat stage 2-3 CKD in cats and moderate to severe PH in dogs. For cats, it helps stabilize kidney function, while for dogs, it addresses symptoms like weakness, exercise intolerance, and syncope associated with heart or respiratory conditions. Its use has expanded to include vascular disorders, and it is also being studied for conditions like patent ductus arteriosus (PDA).

Hero Veterinary imports specific Beraprost variants like RAPROS for CKD, helping over 12,000 pets worldwide through its partnerships with more than 300 clinics.

What Is the Dosage for Beraprost?

For cats with CKD, the standard dosage is 55µg (one tablet) twice daily. For dogs, the typical dose is approximately 15µg/kg twice daily. These doses may be adjusted based on individual response and veterinary guidance. Hero Veterinary provides expert support to ensure safe and effective treatment protocols for both species.

Clinical trials have shown that Beraprost remains effective up to a dosage of 30µg/kg in cats and 15µg/kg in dogs, with ongoing monitoring recommended to optimize results.

What Are Beraprost Side Effects?

Beraprost is generally well-tolerated by pets, with rare side effects that may include mild vomiting or slight increases in heart rate, typically within normal ranges. There are no significant adverse effects noted in studies involving cats with CKD or dogs with PH. Veterinary monitoring focuses on hemostasis and blood pressure to ensure safety.

Studies have shown fewer side effects in pets treated with Beraprost compared to placebo, making it a viable long-term option for managing CKD and PH in pets. Should hypotension occur, treatment should be adjusted.

Is Beraprost Safe for Pets?

Yes, Beraprost is considered safe for pets based on clinical trials involving both cats with CKD and dogs with PH. The safety profile is favorable, with no significant changes in blood counts or chemistry, and a low incidence of adverse events. Hero Veterinary ensures that all imported products adhere to rigorous quality control standards, providing peace of mind for veterinarians and pet owners alike.

Contraindications include pets with bleeding tendencies. Always follow veterinary recommendations for dosing and monitoring.

How Effective Is Beraprost?

Beraprost has proven to be highly effective in managing CKD in cats and PH in dogs. In cats, it stabilizes creatinine levels and slows kidney function decline, while in dogs, it improves cardiac function and reduces pulmonary artery pressure. Studies have demonstrated that Beraprost not only improves symptoms but also contributes to better overall survival and quality of life.

Study Type Cats (CKD Outcome) Dogs (PH Outcome)
Double-blind Stabilized sCr [7] Vasodilation [2]
Model-based Renal perfusion improvement PAP reduction [6]
Long-term Better survival outcomes Improved function

Hero Veterinary Expert Views

"At Hero Veterinary, we integrate Beraprost into treatment protocols for complex conditions such as CKD in cats and PH in dogs. With a team of over 30 professionals and our strong focus on research and development, we are proud to import innovative therapies that improve the lives of companion animals. We serve over 12,000 pets worldwide, ensuring that Beraprost contributes to better health outcomes globally."
— Dr. Elena Wong, Lead Veterinarian, Hero Veterinary

When Should You Use Beraprost?

Beraprost should be used for cats diagnosed with stage 2-3 CKD and dogs with moderate to severe PH. Diagnosis should be confirmed through blood tests, echocardiograms, or IRIS staging for cats. Beraprost is typically used alongside other therapies like sildenafil for PH.

Consult with your vet to ensure the best course of treatment, especially in cases of comorbidities.

Can Beraprost Treat Other Pet Conditions?

While Beraprost is primarily used for CKD in cats and PH in dogs, emerging research supports its use in treating other vascular disorders such as arteriosclerosis or reperfusion injury. Hero Veterinary is actively exploring its potential for treating more complex conditions, including certain cancers and intractable diseases.

In summary, Beraprost provides a targeted, effective treatment for CKD and PH in pets. Key takeaways: its dual action supports better organ function and symptom relief. Actionable advice: Schedule a veterinary consult to determine if Beraprost is right for your pet and monitor progress regularly for optimal results.

FAQs

Is Beraprost approved for dogs?

Beraprost is effective for PH in dogs but is not widely approved for all conditions. It should be used off-label under veterinary supervision.

How long does Beraprost take to work?

Effects are typically noticeable within weeks, with full benefits appearing after 1-6 months, depending on the pet's condition.

Can Beraprost cure CKD?

Beraprost does not cure CKD but helps slow its progression and improve kidney function.

Is Beraprost expensive for pets?

Cost varies, but Hero Veterinary’s partnerships with clinics help make Beraprost more accessible.

What if my pet misses a dose?

If you miss a dose, give the next dose as scheduled, but do not double the dose to make up for it.