Clopidogrel (Generic Plavix) - Anti-Platelet Medication

Clopidogrel (Generic Plavix) - Anti-Platelet Medication

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Clopidogrel is a powerful anti-platelet medication commonly prescribed by veterinarians to prevent unwanted blood clots (thrombi) in cats and dogs. It is especially valuable in cats with hypertrophic cardiomyopathy (HCM), a history of aortic thromboembolism (ATE or “saddle thrombus”), or other conditions that increase the risk of life-threatening clot formation. In dogs, it is used for conditions such as immune-mediated haemolytic anaemia (IMHA), hypercoagulable states, or after certain cardiac procedures.

⭐ Key Benefits

Significantly reduces the risk of arterial thromboembolism in cats (often more effective and better tolerated than aspirin)
Helps prevent clot formation in high-risk dogs
Once-daily dosing and easy to administer (¼ of a 75 mg tablet is a common cat dose)
Generally better gastrointestinal tolerance than aspirin

💊 Usage & Dosage

Give with or without food. Can be given whole or crushed and mixed with a small amount of wet food. Use a pill splitter for accurate ¼-tablet dosing in cats.

Cats: 18.75 mg (¼ of a 75 mg tablet) once daily
Dogs: 1-2 mg/kg once daily (often 75 mg for large dogs, adjusted by weight)

⚠️ Side Effects

Rare but may include: vomiting, decreased appetite, or bleeding (bruising, nosebleeds, blood in stool/urine)
Contact your vet immediately if you notice any signs of bleeding

❗ Importance

Do not stop suddenly without veterinary guidance
Regular blood work may be recommended to monitor response and safety
Keep out of reach of children and never use human prescriptions without veterinary approval

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