Palladia® (Toceranib Phosphate) - Targeted Anti-Cancer Therapy for Dogs & Cats

Targeted Anti-Cancer Therapy for Dogs and Cats

A cancer diagnosis in your pet is one of the most difficult moments a pet owner can face. Palladia® (Toceranib Phosphate) is an FDA-approved targeted tyrosine kinase inhibitor (TKI) that attacks cancer at the molecular level — blocking tumor growth signals and cutting off the blood supply tumors need to grow, while minimizing damage to healthy tissue.

How Palladia® Works

Palladia selectively inhibits tyrosine kinase receptors — proteins that cancer cells rely on to receive growth signals and stimulate new blood vessel formation (angiogenesis). By blocking these pathways, Palladia:

• Inhibits tumor cell proliferation and survival signaling
• Disrupts tumor angiogenesis — cutting off the blood supply that feeds tumor growth
• Targets cancer at the molecular level rather than broadly attacking all dividing cells

Clinical Applications

• Dogs — Mast Cell Tumors (FDA-approved) — the primary approved indication for recurrent or non-resectable cutaneous mast cell tumors in dogs
• Cats — Off-label oncology use — increasingly used by veterinary oncologists for various feline neoplastic and proliferative diseases under specialist guidance

Why Choose Palladia®?

• FDA-approved targeted therapy — the first receptor tyrosine kinase inhibitor approved for veterinary oncology
• Oral administration — convenient tablet form avoids the need for frequent clinic visits for IV chemotherapy
• Targeted mechanism — selectively attacks tumor signaling pathways, reducing collateral damage to healthy tissue
• Proven clinical efficacy — widely used in veterinary oncology clinics worldwide

Available Strengths

• 10 mg × 30 tablets
• 15 mg × 30 tablets
• 50 mg × 30 tablets

Recommended Use

Palladia® is a prescription veterinary oncology medication that must be prescribed and monitored by a veterinarian or veterinary oncologist. Regular blood work and clinical monitoring are essential during treatment. Handle tablets with care — use gloves and avoid crushing or splitting tablets.