PANOQUELL-CA1 (Fuzapladib Sodium) - Injectable for Acute Canine Pancreatitis

Finally — A Veterinary Treatment That Fights Canine Pancreatitis at Its Source

When your dog is struck by acute pancreatitis, every hour counts. The relentless vomiting, the hunched posture, the refusal to eat — watching your dog suffer through a pancreatitis episode is one of the most distressing experiences a pet owner can face. Conventional supportive care helps, but it doesn't stop the inflammatory cascade tearing through the pancreas.

PANOQUELL-CA1 does.

What Makes PANOQUELL-CA1 Different?

Most pancreatitis treatments focus on managing symptoms — fluids, pain relief, rest. PANOQUELL-CA1 (Fuzapladib Sodium for Injection) takes a fundamentally different approach: it targets the root cause of pancreatic tissue destruction — the flood of neutrophils that invade the inflamed pancreas and cause irreversible damage.

As a leukocyte function-associated antigen-1 (LFA-1) activation inhibitor, PANOQUELL-CA1 blocks neutrophil migration directly at the molecular level. No neutrophil invasion. Less tissue destruction. Faster recovery.

The Science Behind the Relief

In acute canine pancreatitis, the body's own immune cells — neutrophils — are recruited to the inflamed pancreas in overwhelming numbers. Rather than helping, they amplify the damage, releasing destructive enzymes that worsen inflammation and accelerate tissue death. PANOQUELL-CA1 interrupts this process by inhibiting LFA-1, the key adhesion molecule neutrophils use to migrate into tissue. The result: the inflammatory cascade is broken before it can cause lasting harm.

Clinical Recognition & Global Trust

PANOQUELL-CA1 is the international equivalent of Brenda Z (ブリンダZ), the pioneering fuzapladib sodium treatment first developed and introduced in Japan. Its mechanism and efficacy are recognized by veterinary specialists worldwide as a meaningful advancement in acute pancreatitis management — moving beyond symptom control to genuine disease modification.

Product Specifications

• Active Ingredient: Fuzapladib Sodium
• Formulation: Injectable solution
• Pack Size: 4 ml bottle
• Indication: Management of clinical signs in acute canine pancreatitis
• Also known as: Brenda Z / ブリンダZ (Japan)

For Veterinary Use Under Professional Supervision

PANOQUELL-CA1 is a prescription veterinary injectable. Dosing, administration protocol, and treatment duration must be determined by a qualified veterinarian. It is indicated for use during the acute phase of canine pancreatitis, where rapid intervention has the greatest impact on patient outcomes.